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Malignant carcinoid tumor

MedGen UID:
581023
•Concept ID:
C0391970
•
Neoplastic Process
SNOMED CT: Malignant carcinoid tumor (445238008); Malignant carcinoid tumor (1157139005)

Professional guidelines

PubMed

Treatment of metastatic carcinoid tumor with dactinomycin or dacarbazine.
van Hazel GA, Rubin J, Moertel CG
Cancer Treat Rep 1983 Jun;67(6):583-5. PMID: 6861165

Recent clinical studies

Etiology

Determination of safe margin in the surgical pathologic specimens of non-small cell carcinoma of the lung.
Feizi I, Sokouti M, Golzari SE, Gojazede M, Farahnak MR, Hashemzadeh S, Rahimi-Rad MH
Pneumologia 2013 Jan-Mar;62(1):16-8. PMID: 23781567
Varying malignant potential of appendiceal neuroendocrine tumors: importance of histologic subtype.
Hsu C, Rashid A, Xing Y, Chiang YJ, Chagpar RB, Fournier KF, Chang GJ, You YN, Feig BW, Cormier JN
J Surg Oncol 2013 Feb;107(2):136-43. Epub 2012 Jul 5 doi: 10.1002/jso.23205. PMID: 22767417
Malignant carcinoid tumor of the cystic duct: a rare cause of bile duct obstruction.
Felekouras E, Petrou A, Bramis K, Prassas E, Papaconstantinou I, Dimitriou N, Pazaiti A, Tsigris C, Giannopoulos A
Hepatobiliary Pancreat Dis Int 2009 Dec;8(6):640-6. PMID: 20007084
Familial occurrence of carcinoid tumors and association with other malignant neoplasms.
Babovic-Vuksanovic D, Constantinou CL, Rubin J, Rowland CM, Schaid DJ, Karnes PS
Cancer Epidemiol Biomarkers Prev 1999 Aug;8(8):715-9. PMID: 10744132
Amyloid myopathy: clinicopathologic study of 16 cases.
Prayson RA
Hum Pathol 1998 May;29(5):463-8. doi: 10.1016/s0046-8177(98)90061-2. PMID: 9596269

Diagnosis

Varying malignant potential of appendiceal neuroendocrine tumors: importance of histologic subtype.
Hsu C, Rashid A, Xing Y, Chiang YJ, Chagpar RB, Fournier KF, Chang GJ, You YN, Feig BW, Cormier JN
J Surg Oncol 2013 Feb;107(2):136-43. Epub 2012 Jul 5 doi: 10.1002/jso.23205. PMID: 22767417
Malignant carcinoid tumor of the cystic duct: a rare cause of bile duct obstruction.
Felekouras E, Petrou A, Bramis K, Prassas E, Papaconstantinou I, Dimitriou N, Pazaiti A, Tsigris C, Giannopoulos A
Hepatobiliary Pancreat Dis Int 2009 Dec;8(6):640-6. PMID: 20007084
Malignant carcinoid tumor of the common bile duct: report of a case.
Kim DH, Song MH, Kim DH
Surg Today 2006;36(5):485-9. doi: 10.1007/s00595-005-3174-5. PMID: 16633759
Malignant carcinoid tumor of the gallbladder: a case report and review of literature.
Kumar S, Agarwal S, Bhargava SK, Minocha VR
Trop Gastroenterol 1992 Apr-Jun;13(2):78-84. PMID: 1413104
Breast metastasis: an unusual manifestation of a malignant carcinoid tumor.
Harrist TJ, Kalisher L
Cancer 1977 Dec;40(6):3102-6. doi: 10.1002/1097-0142(197712)40:6<3102::aid-cncr2820400652>3.0.co;2-n. PMID: 338142

Therapy

DOTATATE -Avid Bilateral Axilla and Subpectoral Lymphadenopathy Induced From COVID-19 mRNA Vaccination Visualized on PET/CT.
Lu Y
Clin Nucl Med 2021 Nov 1;46(11):931-932. doi: 10.1097/RLU.0000000000003697. PMID: 33795589Free PMC Article
Intractable hypercalcemia due to a metastatic carcinoid secreting parathyroid hormone-related peptide and interleukin-6: response to octreotide.
Barhoum M, Hutchins L, Fonseca VA
Am J Med Sci 1999 Sep;318(3):203-5. doi: 10.1097/00000441-199909000-00019. PMID: 10487414
Acromegaly from ectopic growth hormone-releasing hormone secretion by a malignant carcinoid tumor. Successful treatment with long-acting somatostatin analogue SMS 201-995.
Barkan AL, Shenker Y, Grekin RJ, Vale WW
Cancer 1988 Jan 15;61(2):221-6. doi: 10.1002/1097-0142(19880115)61:2<221::aid-cncr2820610203>3.0.co;2-3. PMID: 2891432
Phase II trial of rDNA alfa 2b interferon in patients with malignant carcinoid tumor.
Smith DB, Scarffe JH, Wagstaff J, Johnston RJ
Cancer Treat Rep 1987 Dec;71(12):1265-6. PMID: 3690534
Response of metastatic malignant carcinoid tumor to adriamycin (NSC-123127).
Solomon A, Sonoda T, Patterson FK
Cancer Treat Rep 1976 Mar;60(3):273-6. PMID: 1260782

Prognosis

Determination of safe margin in the surgical pathologic specimens of non-small cell carcinoma of the lung.
Feizi I, Sokouti M, Golzari SE, Gojazede M, Farahnak MR, Hashemzadeh S, Rahimi-Rad MH
Pneumologia 2013 Jan-Mar;62(1):16-8. PMID: 23781567
Varying malignant potential of appendiceal neuroendocrine tumors: importance of histologic subtype.
Hsu C, Rashid A, Xing Y, Chiang YJ, Chagpar RB, Fournier KF, Chang GJ, You YN, Feig BW, Cormier JN
J Surg Oncol 2013 Feb;107(2):136-43. Epub 2012 Jul 5 doi: 10.1002/jso.23205. PMID: 22767417
Malignant carcinoid tumor of the appendix with liver and lung metastasis: report of a case with a high level of serum carcinoembryonic antigen.
Panomreongsak P, Sthapanachai C, Sukpanichnant S, Thakerngpol K, Sattawatthamrong Y, Wongsurakiat P, Wongwanit C, Seesillapachai P
J Med Assoc Thai 2000 Jan;83(1):97-102. PMID: 10710876
Familial occurrence of carcinoid tumors and association with other malignant neoplasms.
Babovic-Vuksanovic D, Constantinou CL, Rubin J, Rowland CM, Schaid DJ, Karnes PS
Cancer Epidemiol Biomarkers Prev 1999 Aug;8(8):715-9. PMID: 10744132
Malignant carcinoid tumor of the gallbladder: a case report and review of literature.
Kumar S, Agarwal S, Bhargava SK, Minocha VR
Trop Gastroenterol 1992 Apr-Jun;13(2):78-84. PMID: 1413104

Clinical prediction guides

Familial occurrence of carcinoid tumors and association with other malignant neoplasms.
Babovic-Vuksanovic D, Constantinou CL, Rubin J, Rowland CM, Schaid DJ, Karnes PS
Cancer Epidemiol Biomarkers Prev 1999 Aug;8(8):715-9. PMID: 10744132
Acromegaly from ectopic growth hormone-releasing hormone secretion by a malignant carcinoid tumor. Successful treatment with long-acting somatostatin analogue SMS 201-995.
Barkan AL, Shenker Y, Grekin RJ, Vale WW
Cancer 1988 Jan 15;61(2):221-6. doi: 10.1002/1097-0142(19880115)61:2<221::aid-cncr2820610203>3.0.co;2-3. PMID: 2891432
Malignant carcinoid tumor altered reactivity of the skin to serotonin in two patients.
ROTBART M
Calif Med 1958 Feb;88(2):112-3. PMID: 13500214Free PMC Article

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